How People Decide if Acne Treatment is Effective

-From 2016, articles commented in the Journal and Focus will be posted here (selection by Prof. JH Saurat M.D.)

How People Decide if Acne Treatment is Effective

Postby CFH » Mon Aug 07, 2017 6:22 pm

Prioritizing treatment outcomes: How people with acne vulgaris decide if their treatment is working.
Layton AM, Whitehouse H, Eady EA, Cowdell F, Warburton KL, Fenton M.
J Evid Based Med. 2017 Apr 26. doi: 10.1111/jebm.12249.

Goal: To measure what people consider an effective treatment for acne, 145 people with acne (PwA) took part, 897 answered the treatment was effective, and 742 fitted with possible outcomes:

-More than a third said that there were fewer spots.
-A fifth said it was less redness.
-Around one in seven said it was a reduction in spot size and around the same proportion said it was a reduction in pain/discomfort.

How did patients observe changes ?
-Looking at the skin was the most widely adopted way of assessing (16.3% of people) and Visual Signs were most considered. Symptoms were less used.
Quality of life was only infrequently mentioned

1.objective measurements run in trials (lesion counts, severity) do not include measurements done by patients at a single point in time, which can include psychosocial well-being and mood. Further studies will need to take this into account.
2. The authors use the term “People with Acne (PwA)” as Acne affects not only patients; many manage themselves and never see a doctor.

Study from UK, a quarter of those who responded lived outside of the UK

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